Â鶹APP

The Department of Chemistry's 2024 Kilpatrick Lecture will be held at 3 p.m. on April 16 at Pritzker Science Center Room 111, and will feature a guest speaker on Innovations in urodynamics

• Margot S. Damaser, Professor of Biomedical Engineering, Cleveland Clinic Lerner College of Medicine

Zoom link to attend this event: 

Damaser will present "Innovations in Wireless Catheter-Free Monitoring of Bladder Function":

• Urodynamics is the gold standard diagnostic test to assess lower urinary tract function and
  dysfunction. However, it has pitfalls because it is a non-physiologic test performed in an artificial
  setting and often is unable to replicate the symptoms that concern patients. To address the
  limitations of Urodynamics and provide for chronic monitoring of bladder function, we have
  developed a wireless catheter-free device for measurement of bladder function without catheters
  or retrograde filling. We designed flexible electronics to wirelessly transmit bladder pressure to a
  small radio receiver taped to the subject’s abdomen. The radio receiver stores the data and
  simultaneously transmits it wirelessly to a nearby laptop using Bluetooth. We have tested this
  system on the bench, in animals, and in an initial acute human subject study in women with
  overactive bladder. This is the first example of a wireless catheter free bladder pressure data
  collection in humans, enabling them to void on a toilet in private while diagnostic data is collected.
  The small, flexible device inserted into the bladder to measure bladder pressure is not painful,
  does not impede urinary flow, and can be easily inserted and extracted. This system could be
  used in conjunction with uroflow and pelvic floor electromyogram for a more complete
  assessment, potentially at home. In addition, the system enables chronic monitoring for closed
  loop neuromodulation, sensory restoration, close titration of pharmaceutical treatments, as well
  as biofeedback. Recent results and future directions will be discussed in the presentation.

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